Personalized Micro-Organs for Improving Human Health

 3-D Human micro tissue technologies accelerating personalized drug discovery and development.
These innovations assist our partners deliver better medicines faster and cost effectively.

Precision Medicine Developer Using Patient-Derived 3D Micro-Tissues

InvivoSciences, Inc. (IVS) is a precision medicine company personalizing the drug development process by introducing patient-derived and gene-edited human samples, including 3D engineered micro-tissues. Our unique integration of cell & tissue handling automation, tissue phenotyping assays, computational biology (AI), and human organ/tissue data enables rapid identification of safety and efficacy profile of a given treatment for specific patient group cost-effectively before expensive clinical trials. IVS’s technology for matchmaking the best treatment for the patient group will expedite the early discovery and clinical trials as well as support post-product launch monitoring. 

John’s Micro Hearts Find The Best Treatment for John

Our founders’ personal experience drove us to start doing what we do now. Thanks to the US National Institute of Health and generous contributors. Their long-term and extensive support enabled IVS to develop and validate human induced pluripotent stem cell (iPSC) derived micro-heart tissue called NuHeart™. IVS’s core competencies include an automated process of mass-producing micro NuHearts™ derived from various lines of patient-specific and gene-edited iPSCs and their high-throughput phenotypic assay platform.

Illustration courtesy of TEDx Talk

Why we do what we do?

InvivoSciences, Inc. (IVS’s) vision is to transfom Biopharmaceutical companies to safe and effective precision medicine providers for patients in a wide range of therapeutic areas including cardiac, cancer, and rare diseases. ISV provides patented, automated human organ-on-a-chip predictive assay technology platforms for drug development. We can also perform reliable toxicity screening rapidly, accurately, and cost effectively.

InvivoSciences, Inc. develops personalized Micro-Organs for improving Human Health. IVS offers phenotypic analysis using its personalized organotypic human samples for accurate prediction of patient-specific safety and efficacy of drug candidates for the pre-clinical development of personal biopharmaceutical products and their safety analysis. InvivoSciences, Inc. is an innovative drug discovery company with pre-clinical program partnerships in heritable cardiomyopathies and cardio-oncology.

IVS’s core competencies include an automated process of mass-producing micro NuHearts derived from various lines of patient-specific and gene-edited iPSCs and their high-throughput phenotypic assay platform.

Areas of Contribution

Aging Heart Research and Cardiac Precision Medicine Development

Rare Diseases Precision Medicine Development

Cardiac Safety Pharmacology
Cardio-Oncology

Technology Applications

HTP Phenotyping

A unique combination of our pioneering biomechanical assays and ultra-rapid optical devices collects high-content data of cell and tissue physiology.

Rare Disease Modeling

Using human induced pluripotent stem cell and gene-editing technologies, IVS supports generation organ models that recapitulate mono-genetic disorders.

Automation

Standardized cell and tissue sample preparations set us apart. IVS developed automated cell and tissue handling device to reduce variability among scientists.

System Biology and AI

The power of artificial intelligence (AI) can be unleashed only if AI have enough data. InvivoSciences is collecting and analyzing the big data to train the AI to predict physiological responses of a given treatment.

Read our White Paper

Human Engineered Tissue:

Medical Countermeasures For Public Health
& CBRN Emergencies

Read now

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